chronic traumatic encephalopathy

noun

: a progressive neurological disease that is found especially in athletes (such as boxers, wrestlers, or football players) who have experienced repetitive, mild injury to the brain and that is characterized by short-term memory loss, concentration deficits, confusion, depression, behavioral and personality changes (such as an increase in irritability, impulsivity, or aggression), speech and gait abnormalities, parkinsonism, and dementia

—abbreviation CTE

called also dementia pugilistica, punch-drunk syndrome

Note: The neurological deterioration of chronic traumatic encephalopathy is accompanied by atrophy of the frontal and temporal lobes and accumulation of tau protein in neurofibrillary tangles.

Examples of chronic traumatic encephalopathy in a Sentence

Recent Examples on the Web

The gunman who killed four people in an NYC office building in July had chronic traumatic encephalopathy (CTE), according to the New York City medical examiner’s office. —Jodi Guglielmi, Rolling Stone, 27 Sep. 2025

Like Mangione, Tamura left behind a piece of evidence for investigators to find, blaming the NFL and football for causing chronic traumatic encephalopathy. —Michael Ruiz, FOXNews.com, 18 Sep. 2025

Medical insurance that includes long-term coverage for chronic traumatic encephalopathy (CTE), mental health support, Title IX compliance, and even post-career transition programs are emerging as major priorities. —Jim Martin, Denver Post, 13 Aug. 2025

Authorities found a note in Tamura’s wallet that, according to The New York Times, criticized the NFL for concealing the sport’s safety issues, particularly regarding chronic traumatic encephalopathy. —Jayna Bardahl, New York Times, 1 Aug. 2025

Word History

First Known Use

1957, in the meaning defined above

Rhymes for chronic traumatic encephalopathy

• cardiomyopathy
• coagulopathy
• homoeopathy
• polyneuropathy
• radiculopathy
• enteropathy
• myelopathy
• retinopathy
• myopathy
• psychopathy

Medical Definition

chronic traumatic encephalopathy

noun

: a progressive neurological disease that is found especially in athletes (as boxers, wrestlers, or football players) who have experienced repetitive, typically minor injury (as concussion) to the brain and is characterized by short-term memory loss, concentration deficits, confusion, depression, behavioral and personality changes (such as an increase in irritability, impulsivity, or aggression), speech and gait abnormalities, parkinsonism, and dementia

—abbreviation CTE

called also dementia pugilistica, punch-drunk syndrome

Note: The neurological deterioration of chronic traumatic encephalopathy is accompanied by atrophy of the frontal and temporal lobes and accumulation of tau protein in neurofibrillary tangles.

… it is only in the past decade that scientists have identified the problem in American football players. They have also been able to identify, on autopsy, pathological markers for the disease, now called chronic traumatic encephalopathy …

—Jeffrey Bartholet, Scientific American

[Dr. Robert] Cantu said that symptoms of chronic traumatic encephalopathy include depression and erratic behavior, but he declined to speculate on any role the condition played in Benoit's final violent acts.

—Alan Schwarz, The New York Times